Synonyma: Benzene, 2,4-dichloro-1-methyl-; DICHLOROMETHYLBENZENE;1,3-DICHLORO-4-METHYLBENZENE;2,4-dichloro-1-methyl-benzen

CAS Number: 95-73-8
Formulae hypotheticae: C7H6Cl2
Pondus hypotheticum: 161.03
EINECS number: 202-445-8

Genera cognata:agriculturae et environmental producta vexillum; triazole fungicides; fungicide intermedia; intermedia pesticide; organici materias rudis; mediis; intermedia organica; Organica; Aryl; C7; Halogenated Hydrocarbonum; Aromata; Building Blocks; Chemicalbook Synthesis Chemical; Hydrogenated Hydrocarbonum; OrganicBuildingBlocks; analytica vexillum products; Organicum aedificium cuneos, pesticidesintermediate; Halogenated hydrocarbonum, Organicum chemical rudis materiae.

2,4-Dichlorotoluene usus et synthesis methodus
Proprietates chemica: hyalinae et perspicuae liquoris.
Utere:
1) Usus ut intermedia pesticidum, tincturarum et pharmaceuticarum, quae in productione 2,4-dichlorobenzaldehydae adhibentur, medicamenta ut adipinum, buprofenum, etc.
2) 2,4-Dichlorotoluene media est inter bactericidarum diniconazolum et benzylchlorotriazolum, atque etiam liber chemicus materia rudis ad praeparationem 2,4-dichlorobenzaldehydae est.
3) Materia rudis synthetica organica, adhibita in pharmaceutica industria ad medicamenta antimalaria producenda, Adepine et synthesis acidi ventralis. Usus est in intermedia pesticide ad fabricandum chloridum 2,4-dichlorobenzyl, chloridum 2,4-dichlorobenzoylum, et acidum 2,4-dichlorobenzoicum.

Duae sunt rationes syntheticae producendi modos.
1. Methodus 1.2,4-dichlorotoluene 2,4-diaminotoluene ut materia rudis utitur, et per diazotizationem et chlorinationem obtinetur. Acidum hydrochloricum et aquam in ollam reactionem pone, calorem ad 50℃, dissolve sub excitatione 2,4-diaminotoluene, pone acidum hydrochloricum et chloridum cuprum in ollam, adde solutionem nitritae sodium 1% aequaliter in Chemicalbook , Temperatura conservatur apud circiter 60 , sta pro propagatione, productum crudum inferius lavatur aqua, donec neutrum sit, alcali additur alcali, deinde aqua lotum ad alcali removendum, crudum 2,4-dichlorotoluene separatum; operis vapor est decocta. . Methodus 2.3-chloro-4-toluidine obtinetur per reactionem diazotizationis cum nitrite sodium, et Sandmeyer reactionem cum chloride cupro.

2.Modus productionis eiusque modi praeparatio sunt hae. In methodo parachlorotoluene, p-chlorotoluene et catalysta ZrCl4 in reactorem ponuntur, et gas chlorinum inflammetur ad reactionem chlorinationis perficiendam. Moles gasi chlorini ad finem reactionis regitur et reactio finitur. Impetratum reactant 85.1% of 2,4-dichlorotoluene continet. Si FeCl3 adhibetur catalysta ad perficiendum reactionem chlorinationis in 10-15, donec relativum solutionis densitas sit 1,025, productum continet 2,4-dichlorotoluene et 3,4-dichlorotoluene ac massam rationem utriusque. components est 100:30. Expleto chlorinatione, aqua ad neutralitatem ablue, et cum solutione 10% NaOH in 100～110 tracta, ut alias immunditias removeas. Tractatum chloridum rectificatur et separatum in turri rectificationis altae (2,4-dichloro Toluene bp200°C, 3,4-dichlorotoluene bp207°C). Proventus 2,4-dichlorotoluene et 3,4-dichlorotoluene 64,4% et 19,8%, respective. Methodus ortho-chlorotoluene o-chlorotoluene utitur chloride sulphureo ut agente chlorinato ad chlorinationem reactionem in 142～196 carry perficiendam. Producta sunt 2,4-dichlorotoluene et 2,3-dichlorotoluene, et inordinata Compositio materiarum rudium 55%, 6%, 39%, respective. Post distillationem (2,4-dichlorotoluene bp 200°C, 2,3-dichlorotoluene bp 207-208°C, o-chlorotoluene bp 157-159°C), 2,4-dichlorotoluene separata est. Methodus Ortho-nitrotoluene Ortho-nitrotoluena chlorinatur coram catalyst FeCl3 in 35～40℃. Cum densitas relativa reactantis attingit 1.320 (15℃), materiam ad neutrum lavandum, et reactantem continet 15% materiae rudis, 2-chloro-6-nitrotoluenae 49%, 4-chloro-2-nitrotoluenae 21% , et 15% polychloride, post rectificationem et crystallizationem tractandi, liber chemicus ad 2-chloro-6-nitrotoluenum Procedit 4-chloro-2-nitrotoluena et 4-chloro-2-nitrotoluena sunt 50% et 30% respective. 4-chloro-2-nitrotoluenum obtinetur per reductionem hydrogenii reactionem et distillationem vaporis ad 4-chloro-2-amino obtinendam. Toluene, diazotizationem et CH2Cl2 addit pro Sandmeyer reactionem ad obtinendum 2,4-dichlorotoluene. Methodus adhibetur ad 4-chloro-2-nitrotoluenam producendam quae est per productionem 2-chloro-6-nitrotolueni (ut media usus herbicidi quinclorac). 2,4-Diaminotoluene Methodus 2,4-Diaminotoluene reactionem diazotizationis coram acidi NaNO2 et hydrochlorici patitur, ac deinde Sandmeyer reactionem in praesentia Cu2Cl2 obtinet, ut 2,4-dichlorotoluene obtineat. Acidum 3-chloro-4-methylaninum 3-chloro-4-methylaninum et hydrochloricum reactioni ahenum accedunt, NaNO2 solutio aquea dropwise in 3-5℃ additur, et additio intra 2-3h pro diazotizatione Post peractam. reactionem, liquor diazotizatus guttatim additur solutioni acidi hydrochlorici continens Cu2Cl2 ad 2-5°C ad faciendam reactionem Sandmeyer ad obtinendam 2,4-dichlorotoluenam. Inter methodos supra modos, chloride producta utendo p-chlorotoluene et o-chlorotoluene sicut materia rudis multas immunditias continet et similia puncta fervefacta habet. Necesse est ut turres rectificans altae efficientiae utantur ad fractiones quam ad obtinendum plus 98% of 2,4-dichlorotoluene. Hae duae rationes difficiles sunt ad operandum, et apparatus est princeps investment sumptus. Methodus 2.4-diaminotoluene industrialisationi apta non est, et methodus o-nitrotoluena et methodus 3-chloro-4-methylanilina ad parandum 2,4-dichlorotoluene eadem principia fundamentalia habent, et utrumque diazotizationem requirunt et Sandmeyer Respondentes. ibi defectio aquarum vastioris. Methodus o-nitrotoluene ad 2-chloro-6-nitrotoluenam co-producendam adhibetur, quae adhuc ad 2-chloro-6-aminotoluenam obtinendam reducitur, quae media est momenti ad herbicidium quinclorac producendum.